Microplastics menace: Study reveals hidden lung threats
Inhaled microplastics can weaken immune cells in the lungs, increasing the risk of diseases, according to scientists from the University of Pittsburgh. These particles may lead to long-term health issues.
What do you need to know?
- Microplastic affects lung health: Researchers from the University of Pittsburgh found that inhaled microplastic particles weaken macrophages, key immune cells in the lungs.
- Threat to the entire body: Research indicates that microplastics can spread throughout the body, affecting various organ systems and increasing the risk of diseases.
During the ATS 2025 International Conference in San Francisco, scientists presented their findings on the impact of microplastics on health. Prof. Adam Soloff, the study's author, said that it's eye-opening knowledge. It shows that while microplastics are not the most dangerous factor we can encounter, they are certainly not inconsequential.
How does microplastic affect the body?
Macrophages, the most numerous immune cells in the lungs, are responsible for engulfing pathogens and maintaining tissue homeostasis. Studies have shown that within 24 hours of exposure to microplastics, macrophages were less able to surround and engulf bacteria.
Prof. Soloff warns that microplastics present in the airways, after passing through the lungs, spread systemically and negatively impact the function of macrophages.
Is there a way to protect against microplastics?
Prof. Soloff says that given the poor air quality in so many places around the world, one could imagine that developing an inexpensive therapy with a low risk of side effects, which would restore lung macrophage function, could be a valuable tool in the fight against the growing incidence of lung diseases.
The research team now plans further studies on lung tissues of patients exposed to microplastics. The long-term goal is to develop biomarkers for lung disease risk, which could be used for early detection or intervention.
