Debunking the myth: Drinking coffee on an empty stomach - who really should avoid it?

Moreover, caffeine reduces histamine levels (linked to allergic reactions) and expands the bronchi (providing relief for those with asthma).

Interestingly, a cup of black coffee holds more antioxidants than a glass of orange juice. Therefore, its consumption is often related to anti-aging effects and the reduction in the risk of developing type 2 diabetes, cancer, Parkinson's, and Alzheimer's disease.

Furthermore, it positively impacts metabolism, improves intestinal peristalsis, and potentially aids in weight loss.

Caffeine can elevate blood pressure, but only if its recommended daily dosage of 400mg for an adult is surpassed. Typically, 400 mg is equivalent to four cups of coffee per day.

Notably, coffee functions as a diuretic. This means that, if over-consumed, it may cause dehydration.

Nevertheless, some individuals experience irritability after consuming just a solitary cup of coffee, in addition to stomach aches and headaches. Consequently, it's no wonder that the myth concerning the harm of coffee consumption on an empty stomach could gain traction amongst them.

The problem arises when scientific studies fail to support this theory of a negative effect on the intestines and stomach from coffee consumption on an empty stomach.

Individuals who report side effects from consuming even minimal amounts of coffee are not fabricating their experiences.

The metabolism of caffeine chiefly occurs in the liver with the involvement of the enzyme cytochrome P450 (isoenzyme 1A2). Some people possess this enzyme so much that caffeine is effectively metabolized.

However, others have a significantly less active enzyme, causing caffeine to remain in their bloodstream for a prolonged period, leading to the above side effects.

This disparity is mainly due to genetic factors but can be influenced by medication intake, general health (coffee can irritate the stomachs of people with inflammation of the gastric mucosa or gastric ulcers), age, and smoking habits. Thus, how the body responds to caffeine depends on individual variations.

Since the 1970s, scientists have been studying the benefits and harm of coffee consumption, especially in relation to the intestines. They have not found any evidence that coffee irritates the stomach, as reported by "The New York Times".

The American Gastroenterological Association adds that the stomach has several effective methods of guarding against irritative substances. In the majority of cases, coffee will not pose harm to it.